Via San Antonio: I-37/281 south, take exit 72 about 75 miles outside of San Antonio to Three Rivers and continue south all the way into Edinburg, take 83 West to Mission.
Via Houston/Corpus Christi: Take 59 South through Victoria & Kingsville to Rivera then turn west (right) on 285 to Falfurrias then go south on 281 to Edinburg, take 83 West to Mission.
Traveling the skyways, visitors can fly into either of the two international airports in the Rio Grande Valley, McAllen's Miller International Airport (just ten minutes from Mission) or the Valley International Airport in Harlingen (an hour's drive from Mission).
Miller International Airport
2500 S. Bicentennial
McAllen, TX 78501
Tel. (956) 682-9101
Valley International Airport
Airport Terminal Building
Harlingen, TX 78550
Tel. (956) 430-8600
Continental Airlines (McAllen and Harlingen)
American Airlines (McAllen only)
Southwest Airlines (Harlingen only)
800-435-9792 - En Espanol 800-826-6667